Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzyloxycarbonyl-L-phenylalanyl-L-lysyl-acyloxyketone | - |
Porphyromonas gingivalis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Porphyromonas gingivalis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Nalpha-benzyloxycarbonyl-L-lysine 4-nitroanilide + H2O | - |
Porphyromonas gingivalis | Nalpha-benzyloxycarbonyl-L-lysine + 4-nitroaniline | - |
? | |
thrombomodulin + H2O | Lys-gingipain and Arg-gingipain cleave thrombomodulin in vitro | Porphyromonas gingivalis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
KGP | - |
Porphyromonas gingivalis |
Lys-gingipain | - |
Porphyromonas gingivalis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Porphyromonas gingivalis |
General Information | Comment | Organism |
---|---|---|
physiological function | gingipains induce the degradation and inactivation of endothelial thrombomodulin which may promote vascular coagulation and inflammation | Porphyromonas gingivalis |