Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
bradykinin + H2O | Porphyromonas gingivalis | together with gingipain R, gingipain K induces vascular permeability enhancement in human plasma by cleaving bradykinin from high molecular weight kininogen | fragments of bradykinin | - |
? | |
Fibrinogen + H2O | Porphyromonas gingivalis | most prominent target among plasma proteins | Fragments of fibrinogen | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Porphyromonas gingivalis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
bradykinin + H2O | together with gingipain R, gingipain K induces vascular permeability enhancement in human plasma by cleaving bradykinin from high molecular weight kininogen | Porphyromonas gingivalis | fragments of bradykinin | - |
? | |
Fibrinogen + H2O | prominent target among plasma proteins | Porphyromonas gingivalis | Fragments of fibrinogen | - |
? | |
Fibrinogen + H2O | most prominent target among plasma proteins | Porphyromonas gingivalis | Fragments of fibrinogen | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | the predominant form of gingipain K is a complex of the 60000 Da catalytic domain with hemagglutinins, enzyme is build of a prepropeptide, a catalytic domain and a hemagglutinin domain | Porphyromonas gingivalis |
Synonyms | Comment | Organism |
---|---|---|
porphypain | - |
Porphyromonas gingivalis |