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Literature summary for 3.4.22.40 extracted from

  • Montoya, S.E.; Thiels, E.; Card, J.P.; Lazo, J.S.
    Astrogliosis and behavioral changes in mice lacking the neutral cysteine protease bleomycin hydrolase (2007), Neuroscience, 146, 890-900.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus Q8R016 studies on BLMH knockout mice, B6.129Blmhtm1Geh/J null animals
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Source Tissue

Source Tissue Comment Organism Textmining
central nervous system histological examination, increase in GFAP-positively stained astroglia observed in the brains of aged null mice compared with wild-type controls Mus musculus
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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role of bleomycin protease in the brain analyzed, behavioral phenotype of knockout mice studied using multiple behavioral paradigms, physiological non-redundant function for bleomycin hydrolase in the CNS suggested Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information immunohistochemical analysis and behavioral phenotyping of mice with a targeted deletion of the neutral cysteine protease described Mus musculus ?
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?

Synonyms

Synonyms Comment Organism
BLMH protein
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Mus musculus