Literature summary for 3.4.22.38 extracted from

Gu, X.; Peng, Y.; Zhao, Y.; Liang, X.; Tang, Y.; Liu, J.
A novel derivative of artemisinin inhibits cell proliferation and metastasis via down-regulation of cathepsin K in breast cancer (2019), Eur. J. Pharmacol., 858, 172382 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
SM934-testosterone	inhibits proliferation and metastasis ability of breast cancer cells via inhibiting the expression of cathepsin K followed by the inhibition of Bcl-xL	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P43235	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
MDA-MB-231 cell	-	Homo sapiens	-
SK-BR-3 cell	-	Homo sapiens	-

Expression

Organism	Comment	Expression
Homo sapiens	SM934-testosterone inhibits proliferation and metastasis ability of breast cancer cells via inhibiting the expression of cathepsin K followed by the inhibition of Bcl-xL	down

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Release 2023.1 (January 2023)