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Literature summary for 3.4.22.38 extracted from

  • Morko, J.; Kiviranta, R.; Mulari, M.T.; Ivaska, K.K.; Vaeaenaenen, H.K.; Vuorio, E.; Laitala-Leinonen, T.
    Overexpression of cathepsin K accelerates the resorption cycle and osteoblast differentiation in vitro (2009), Bone, 44, 717-728.
    View publication on PubMed
Search for more literature for 3.4.22.38

Protein Variants

Protein Variants Comment Organism
additional information construction of transgenic UTU17 mice, overexpression of cathepsin K accelerates the resorption cycle and osteoblast differentiation in vitro, cathepsin K overexpression enhances osteogenesis and induces the formation of exceptionally small, actively resorbing osteoclasts from their bone marrow precursors in vitro, intracellular mechanisms, overview. The number of cathepsin K-containing vesicles in UTU17+/+ osteoclasts is highly increased Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Mus musculus 5764
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
collagen I + H2O Mus musculus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 gene Ctsk
-

Source Tissue

Source Tissue Comment Organism Textmining
bone
-
 Mus musculus
-
bone marrow cell line
-
 Mus musculus
-
osteoclast
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
collagen I + H2O
-
 Mus musculus ?
-
 ?