Literature summary for 3.4.22.38 extracted from

Samokhin, A.O.; Wong, A.; Saftig, P.; Broemme, D.
Role of cathepsin K in structural changes in brachiocephalic artery during progression of atherosclerosis in apoE-deficient mice (2008), Atherosclerosis, 200, 58-68.

Search for more literature for 3.4.22.38

Application

Application	Comment	Organism
medicine	cathepsin K is linked to the pathogenesis of osteoporosis, arthritis, cardiovascular and respiratory diseases	Mus musculus

Protein Variants

Protein Variants	Comment	Organism
additional information	the effects of cathepsin K deficiency (ctsK-/-) on atherosclerotic plaque formation in brachiocephalic arteries in an aggressive atherosclerosis model using apoE-deficient mice on cholate-containing high fat diet is examined. Cathepsin K deficiency appears to increase lesion stability in brachiocephalic arteries by maintaining the integrity of the tunica media and by decreasing plaque vulnerability to rupture	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Synonyms

Synonyms	Comment	Organism
cathepsin K	-	Mus musculus

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Release 2023.1 (January 2023)