Inhibitors | Comment | Organism | Structure |
---|---|---|---|
RLMAAKAESRK | competitive inhibitor | Porphyromonas gingivalis | |
RRLMAAKAES | mixed-type inhibitor | Porphyromonas gingivalis | |
RRLMAAKAESR | mixed-type inhibitor | Porphyromonas gingivalis | |
RRLMAAKAESRK | mixed-type inhibitor, the arginine residue at position 15 of the docapeptide substantially contributes to the enzyme-inhibitory activity and the arginine residue at position 14 plays important roles in exerting enzyme-inhibitory activity | Porphyromonas gingivalis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0044 | - |
Z-Phe-Arg-7-amido-4-methylcoumarin | at pH 7.5 and 37°C | Porphyromonas gingivalis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Porphyromonas gingivalis | B2RKK0 | - |
- |
Porphyromonas gingivalis ATCC 33277 | B2RKK0 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Z-Phe-Arg-7-amido-4-methylcoumarin + H2O | - |
Porphyromonas gingivalis | Z-Phe-Arg + 7-amino-4-methylcoumarin | - |
? | |
Z-Phe-Arg-7-amido-4-methylcoumarin + H2O | - |
Porphyromonas gingivalis ATCC 33277 | Z-Phe-Arg + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Arg-gingipain | - |
Porphyromonas gingivalis |
Arg-specific cysteine proteinase | - |
Porphyromonas gingivalis |
RGP | - |
Porphyromonas gingivalis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00096 | - |
RRLMAAKAESRK | at pH 7.5 and 37°C | Porphyromonas gingivalis | |
0.0013 | - |
RRLMAAKAESR | at pH 7.5 and 37°C | Porphyromonas gingivalis | |
0.0013 | - |
RRLMAAKAES | at pH 7.5 and 37°C | Porphyromonas gingivalis | |
0.0099 | - |
RLMAAKAESRK | at pH 7.5 and 37°C | Porphyromonas gingivalis |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.145 | - |
at pH 7.5 and 37°C | Porphyromonas gingivalis | RRLMAAKAESRK | |
0.242 | - |
at pH 7.5 and 37°C | Porphyromonas gingivalis | RRLMAAKAESR | |
0.248 | - |
at pH 7.5 and 37°C | Porphyromonas gingivalis | RLMAAKAESRK |