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Literature summary for 3.4.22.36 extracted from

  • Talanian, R.V.; Quinlan, C.; Trautz, S.; Hackett, M.C.; Mankovich, J.A.; Banach, D.; Ghayur, T.; Brady, K.D.; Wong, W.W.
    Substrate specificities of caspase family proteases (1997), J. Biol. Chem., 272, 9677-9682.
    View publication on PubMed
Search for more literature for 3.4.22.36

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0073
-
 acetyl-YEVD-4-nitroanilide pH 7.5, 30°C Homo sapiens
0.0085
-
 acetyl-LEVD-4-nitroanilide pH 7.5, 30°C Homo sapiens
0.018
-
 acetyl-LEVD-4-nitroanilide pH 7.5, 30°C Homo sapiens
0.023
-
 acetyl-YVAD-4-nitroanilide pH 7.5, 30°C Homo sapiens
0.045
-
 acetyl-DQMD-4-nitroanilide pH 7.5, 30°C Homo sapiens
0.046
-
 acetyl-VEID-4-nitroanilide pH 7.5, 30°C Homo sapiens
0.105
-
 acetyl-YEVDGW-amide pH 7.5, 30°C Homo sapiens
0.12
-
 acetyl-VQVD-4-nitroanilide pH 7.5, 30°C Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-DEVD-4-nitroanilide + H2O
-
 Homo sapiens acetyl-DEVD + 4-nitroaniline
-
 ?
acetyl-DQMD-4-nitroanilide + H2O
-
 Homo sapiens acetyl-DQMD + 4-nitroaniline
-
 ?
acetyl-LEVD-4-nitroanilide + H2O
-
 Homo sapiens acetyl-LEVD + 4-nitroaniline
-
 ?
acetyl-VEID-4-nitroanilide + H2O
-
 Homo sapiens acetyl-VEID + 4-nitroaniline
-
 ?
acetyl-VQVD-4-nitroanilide + H2O
-
 Homo sapiens acetyl-VQVD + 4-nitroaniline
-
 ?
acetyl-YEVD-4-nitroanilide + H2O
-
 Homo sapiens acetyl-YEVD + 4-nitroaniline
-
 ?
acetyl-YEVDGW-amide + H2O preferred peptide substrate Homo sapiens ?
-
 ?
acetyl-YVAD-4-nitroanilide + H2O
-
 Homo sapiens acetyl-YVAD + 4-nitroaniline
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Homo sapiens