Inhibitors | Comment | Organism | Structure |
---|---|---|---|
atorvastatin | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Homo sapiens | 5764 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
macrophage | - |
Homo sapiens | - |
monocyte | - |
Homo sapiens | - |
THP-1 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Hemoglobin + H2O | - |
Homo sapiens | ? | - |
? |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | legumain mRNA is down-regulated in monocytes isolated from patients treated with atorvastatin | down |
Homo sapiens | legumain expression is increased during monocyte-to-macrophage differentiation | up |