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Literature summary for 3.4.22.34 extracted from

  • Alim, M.A.; Tsuji, N.; Miyoshi, T.; Islam, M.K.; Hatta, T.; Yamaji, K.; Fujisaki, K.
    Developmental stage- and organ-specific expression profiles of asparaginyl endopeptidases/legumains in the ixodid tick Haemaphysalis longicornis (2008), J. Vet. Med. Sci., 70, 1363-1366.
    View publication on PubMed
Search for more literature for 3.4.22.34

Localization

Localization Comment Organism GeneOntology No. Textmining
vacuole digestive vacuoles of gut epithelial cells Haemaphysalis longicornis 5773
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Haemaphysalis longicornis recombinant HlLgm and HlLgm2 efficiently digest blood proteins, haemoglobin and bovine serum albumin ?
-
 ?
additional information Haemaphysalis longicornis role of legumain in blood feeding and blood-meal digestion in ticks ?
-
 ?

Organism

Organism UniProt Comment Textmining
Haemaphysalis longicornis
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adult
-
 Haemaphysalis longicornis
-
epithelial cell gut Haemaphysalis longicornis
-
larva
-
 Haemaphysalis longicornis
-
midgut
-
 Haemaphysalis longicornis
-
additional information legumain is not detected in salivary glands, ovaries, cuticles, tracheae, Malpighian tubules and synganglia Haemaphysalis longicornis
-
nymph
-
 Haemaphysalis longicornis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information recombinant HlLgm and HlLgm2 efficiently digest blood proteins, haemoglobin and bovine serum albumin Haemaphysalis longicornis ?
-
 ?
additional information role of legumain in blood feeding and blood-meal digestion in ticks Haemaphysalis longicornis ?
-
 ?

Synonyms

Synonyms Comment Organism
HlLgm
-
 Haemaphysalis longicornis
HlLgm2
-
 Haemaphysalis longicornis
legumain
-
 Haemaphysalis longicornis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 recombinant enzymes digested hemoglobin and bovine serum albumin optimally at pH 7 Haemaphysalis longicornis

pH Range

pH Minimum pH Maximum Comment Organism
additional information
-
 rHlLgm and rHlLgm2 are active at neutral to alkaline pH Haemaphysalis longicornis