Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | inhibitor specificity profiles of cathepsin B and legumain regarded and used for analysis of the suitability of fluorescent activity-based probes | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | involved in lysosomal processing of bacterial antigens for MHC class II presentation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q99538 | Homo sapiens | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
monocyte | RAW264.7 monocyte lysate utilized for monitoring endogenous legumain by designed activity-based probes, lysates from 816 B cells used for detection assay of endogenous legumain | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
positional scanning combinatorial library of peptide acyloxymethyl ketones (AOMKs) to probe subsite specificity of legumain, design of fluorescent activity-based probes indicating high selectivity and cell-permeability for monitoring legumain activity in complex proteome structures, selectivity of optimized legumain probes in intact cells shown, structure of developed probes indicated | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | involved in lysosomal processing of bacterial antigens for MHC class II presentation | Homo sapiens | ? | - |
? | |
additional information | subsite specificity of legumain analyzed to design fluorescent activity-based probes for monitoring endogenous legumain activity | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AEP | - |
Homo sapiens |
Asparaginyl endopeptidase | - |
Homo sapiens |