Protein Variants | Comment | Organism |
---|---|---|
Y289R | inactive, substitution of 2Apro A104 can partially restore self-processing on the mutant Y289R | Human rhinovirus sp. |
Y289R/A104C | substitution of 2Apro A104 can partially restore self-processing on the mutant Y289R | Human rhinovirus sp. |
Y289R/A104S | substitution of 2Apro A104 can partially restore self-processing on the mutant Y289R | Human rhinovirus sp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzyloxycarbonyl-Val-Ala-Asp (OMe)-fluoromethyl ketone | - |
Human rhinovirus sp. | |
benzyloxycarbonyl-Val-Ala-Met-fluoromethyl ketone | - |
Human rhinovirus sp. |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human rhinovirus sp. | - |
serotype 14 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
eukaryotic translation initiation factor 4F p220 subunit + H2O | the 2Apro cleavage site on eIF4GI is TLSTR*GPPR | Human rhinovirus sp. | protein CPa + protein CPb | - |
? |
Synonyms | Comment | Organism |
---|---|---|
2A proteinase | - |
Human rhinovirus sp. |
2Apro | - |
Human rhinovirus sp. |