Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.28 extracted from

  • Yin, J.; Cherney, M.M.; Bergmann, E.M.; Zhang, J.; Huitema, C.; Pettersson, H.; Eltis, L.D.; Vederas, J.C.; James, M.N.
    An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors (2006), J. Mol. Biol., 361, 673-686.
    View publication on PubMed
Search for more literature for 3.4.22.28

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with inhibitors N-acetyl-L-leucyl-alanyl-alanyl-(N,N-dimethyl)-glutamine-fluoromethyl ketone, N-acetyl-L-leucyl-phenylalanyl-phenylalanyl-glutamate-fluoromethyl ketone, and N-acetyl-L-leucyl-alanyl-alanyl-(N,N-dimethyl)-glutamine-(1,4-dioxo-3,4-dihydro-1H-phthalazin-2-yl)methyl ketone Hepatovirus A

Inhibitors

Inhibitors Comment Organism Structure
N-acetyl-L-leucyl-alanyl-alanyl-(N,N-dimethyl)-glutamine-(1,4-dioxo-3,4-dihydro-1H-phthalazin-2-yl)methyl ketone
-
 Hepatovirus A
N-acetyl-L-leucyl-alanyl-alanyl-(N,N-dimethyl)-glutamine-fluoromethyl ketone
-
 Hepatovirus A
N-acetyl-L-leucyl-phenylalanyl-phenylalanyl-glutamate-fluoromethyl ketone
-
 Hepatovirus A

Organism

Organism UniProt Comment Textmining
Hepatovirus A
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Hepatovirus A

Synonyms

Synonyms Comment Organism
3C protease
-
 Hepatovirus A