Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P25774 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cathepsin K + H2O | cathepsin S cleaves cathepsin K (cathepsin cannibalism) which reduces the total elastin- and collagen-degradative activity in the multiple cathepsin system | Homo sapiens | ? | - |
? | |
Collagen + H2O | - |
Homo sapiens | ? | - |
? | |
Elastin + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cathepsin S | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
assay at | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | cathepsin S cleaves cathepsin K (cathepsin cannibalism) which reduces the total elastin- and collagen-degradative activity in the multiple cathepsin system. Cathepsin cannibalism protects type I collagen through a reduction in the amount of highly collagenolytic cathepsin K available due to cathepsin S degradation of cathepsin K | Homo sapiens |