Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endosome | co-localized with CX3CL1 | Homo sapiens | 5768 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CX3CL1 + H2O | Homo sapiens | cathepsin S is able to cleave membrane-anchored CX3CL1, releasing a 55-kDa fragment to the medium | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P25774 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
vascular smooth muscle cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CX3CL1 + H2O | cathepsin S is able to cleave membrane-anchored CX3CL1, releasing a 55-kDa fragment to the medium | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cathepsin S | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | by cleaving membrane-anchored CX3CL1 cathepsin S regulates the adhesion of vascular smooth muscle cells and the capture of monocytes to the sites of atherogenesis | Homo sapiens |