Protein Variants | Comment | Organism |
---|---|---|
additional information | cathepsin S-deficient mutant mice lack the TAP-independent vacuolar pathway of MHC class I crosspresentation, and have reduced crosspriming to particulate and cell-associated antigens as well as to influenza virus, overview | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
leupeptin | - |
Mus musculus | |
additional information | no inhibition by proteasome inhibitors | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endosome | - |
Mus musculus | 5768 | - |
phagosome | - |
Mus musculus | - |
- |
vacuole | - |
Mus musculus | 5773 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | cathepsin S, a cysteine protease, plays an important role in generating peptides for the vacuolar, TAP-independent MHC class I cross-presentation in vivo | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
B-cell | - |
Mus musculus | - |
dendritic cell | - |
Mus musculus | - |
macrophage | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | cathepsin S, a cysteine protease, plays an important role in generating peptides for the vacuolar, TAP-independent MHC class I cross-presentation in vivo | Mus musculus | ? | - |
? |