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Literature summary for 3.4.22.27 extracted from

  • Gour-Salin, B.J.; Lachance, P.; Bonneau, P.R.; Storer, A.C.; Kirschke, H.; Broemme, D.
    E-64 analogs as inhibitors of cathepsin S: Importance of the S2-P2 intercations for potency and selectivity (1994), Bioorg. Chem., 22, 227-241.
No PubMed abstract available
Search for more literature for 3.4.22.27

Inhibitors

Inhibitors Comment Organism Structure
epoxysuccinyl-Ala benzyl ester
-
 Homo sapiens
epoxysuccinyl-Arg benzyl ester
-
 Homo sapiens
epoxysuccinyl-D-Phe benzyl amide
-
 Homo sapiens
epoxysuccinyl-D-Phe benzyl ester
-
 Homo sapiens
epoxysuccinyl-Ile benzyl ester
-
 Homo sapiens
epoxysuccinyl-Leu benzyl amide
-
 Homo sapiens
epoxysuccinyl-Leu benzyl ester
-
 Homo sapiens
epoxysuccinyl-Phe benzyl amide
-
 Homo sapiens
epoxysuccinyl-Phe benzyl ester
-
 Homo sapiens
epoxysuccinyl-Val benzyl ester
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Leu-Arg-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens benzyloxycarbonyl-Leu-Arg + 7-amino-4-methylcoumarin
-
 ?
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
 ?