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Literature summary for 3.4.22.27 extracted from
- Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen I: a kinetic analysis (1998), Biochemistry, 37, 5258-5266.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| cystatin C | - |
Homo sapiens | |
| squamous cell carcinoma antigen 1 | 99% inhibition at 1 mM, interacts with cathespin S at 1:1 stoichiometry, t1/2 of the cathepsin-squamous cell carcinoma antigen 1 complex is above 1155 min | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| lysosome | - |
Homo sapiens | 5764 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (benzyloxycarbonyl-Phe-Arg)2-rhodamine 110 + H2O | - |
Homo sapiens | ? | - |
? |  |
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