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Literature summary for 3.4.22.16 extracted from

  • Bratkovic, T.; Lunder, M.; Popovic, T.; Kreft, S.; Turk, B.; Strukelj, B.; Urleb, U.
    Affinity selection to papain yields potent peptide inhibitors of cathepsins L, B, H, and K (2005), Biochem. Biophys. Res. Commun., 332, 897-903.
    View publication on PubMed
Search for more literature for 3.4.22.16

Inhibitors

Inhibitors Comment Organism Structure
CNWAAGYNCGGGS-NH2 cyclic peptide with intramolecular disulfide bond, comparison of inhibitory effect with cathepsin K, cathepsin L, cathepsin B and papain Homo sapiens
CNWTLGGYKCGGGS-NH2 cyclic peptide with intramolecular disulfide bond, comparison of inhibitory effect with cathepsin K, cathepsin L, cathepsin B and papain Homo sapiens
CWEWGGWHCGGSS-OH cyclic peptide with intramolecular disulfide bond, comparison of inhibitory effect with cathepsin K, cathepsin L, cathepsin B and papain Homo sapiens
CWSMMGFQCGGGS-NH2 cyclic peptide with intramolecular disulfide bond, comparison of inhibitory effect with cathepsin K, cathepsin L, cathepsin B and papain Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0039
-
 CWSMMGFQCGGGS-NH2 pH 6.8, 22°C Homo sapiens
0.0049
-
 CWEWGGWHCGGSS-OH pH 6.8, 22°C Homo sapiens
0.0051
-
 CNWTLGGYKCGGGS-NH2 pH 6.8, 22°C Homo sapiens
0.0179
-
 CNWAAGYNCGGGS-NH2 pH 6.8, 22°C Homo sapiens