Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-naphthalenesulfonyl-Ile-Trp-CHO | reversible inhibitor of cathepsin L | Rattus norvegicus | |
benzyloxycarbonyl-Phe-Phe-fluoromethylketone | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
striatal neuron | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-Phe-Arg-7-amido-4-trifluoromethylcoumarin + H2O | - |
Rattus norvegicus | N-acetyl-Phe-Arg + 7-amino-4-trifluoromethylcoumarin | - |
? |
General Information | Comment | Organism |
---|---|---|
physiological function | cathepsin L plays a role in glutamate receptor-induced nuclear factor-kappa B activation and excitotoxicity in rat striatal neurons | Rattus norvegicus |