Inhibitors | Comment | Organism | Structure |
---|---|---|---|
methyl 5-acetyloxy-dinaphtho[1,2-2'3']furan-7,12-dione-6-carboxylate | furanquinone from Paulownia tomentosa stem, inhibitory to both cathepsin L and cathepsin K | Homo sapiens | |
methyl 5-hydroxy-dinaphtho[1,2-2'3']furan-7,12-dione-6-carboxylate | furanquinone from Paulownia tomentosa stem, inhibitory to both cathepsin L and cathepsin K | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0386 | - |
pH 5.5, 22°C | Homo sapiens | methyl 5-acetyloxy-dinaphtho[1,2-2'3']furan-7,12-dione-6-carboxylate | |
0.0616 | - |
pH 5.5, 22°C | Homo sapiens | methyl 5-hydroxy-dinaphtho[1,2-2'3']furan-7,12-dione-6-carboxylate |