Application | Comment | Organism |
---|---|---|
medicine | survival of patients with colorectal cancer is inversely associated with staining intensity in the epithelial cytoplasm and stromal nuclei. In different colorectal cell lines and in vivo tumors, pro- and active cathepsin L isoforms are present in both the cytoplasm and nuclear samples, with pro-cathepsin L at 50 kDa and active cathepsin L at 25 kDa. Purified nuclear and cytoplasmic fractions show cathepsin L activity | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
nucleus | - |
Homo sapiens | 5634 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
25000 | - |
x * 50000, pro-cathepsin L, x * 25000, mature form, SDS-PAGE | Homo sapiens |
50000 | - |
x * 50000, pro-cathepsin L, x * 25000, mature form, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
patients with colorectal cancer | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colonic cancer cell | - |
Homo sapiens | - |
Subunits | Comment | Organism |
---|---|---|
? | x * 50000, pro-cathepsin L, x * 25000, mature form, SDS-PAGE | Homo sapiens |