Inhibitors | Comment | Organism | Structure |
---|---|---|---|
trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane | i.e. E64 | Streptococcus pyogenes |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Human fibrinogen + H2O | Streptococcus pyogenes | release and processing, the enzyme abolishes the binding of Streptococcus pyogenes to full-length or 30 kDa fragment of human fibrinogen Fn, kinetics overview | ? | - |
? | |
protein F1 + H2O | Streptococcus pyogenes | SpeB modulates fibronectin-dependent internalization of Streptococcus pyogenes by efficient proteolysis of cell-wall-anchored protein F1, e.g. in human pharyngeal epithelial cells Detroit 562, while proteins H and M1 are protected by plasma proteins, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pyogenes | - |
several AP strains | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Human fibrinogen + H2O | processing | Streptococcus pyogenes | ? | - |
? | |
Human fibrinogen + H2O | release and processing, the enzyme abolishes the binding of Streptococcus pyogenes to full-length or 30 kDa fragment of human fibrinogen Fn, kinetics overview | Streptococcus pyogenes | ? | - |
? | |
protein F1 + H2O | SpeB modulates fibronectin-dependent internalization of Streptococcus pyogenes by efficient proteolysis of cell-wall-anchored protein F1, e.g. in human pharyngeal epithelial cells Detroit 562, while proteins H and M1 are protected by plasma proteins, overview | Streptococcus pyogenes | ? | - |
? | |
protein F1 + H2O | cell-wall-anchored protein F1 | Streptococcus pyogenes | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SpeB | - |
Streptococcus pyogenes |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Streptococcus pyogenes |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | - |
assay at | Streptococcus pyogenes |