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Literature summary for 3.4.22.1 extracted from

  • Serveau-Avesque, C.; Ferrer-Di Martino, M.; Herve-Grepinet, V.; Hazouard, E.; Gauthier, F.; Diot, E.; Lalmanach, G.
    Active cathepsins B, H, K, L and S in human inflammatory bronchoalveolar lavage fluids (2006), Biol. Cell., 98, 15-22.
    View publication on PubMed
Search for more literature for 3.4.22.1

Inhibitors

Inhibitors Comment Organism Structure
[N-(L-3-trans-propylcarbamoyl oxirane-2-carbonyl)-L-isoleucyl-L-proline] specific inhibitor Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bronchoalveolar lavage fluid contains the inactive zymogen Homo sapiens
-
lung
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-L-Arg-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens benzyloxycarbonyl-L-Arg + 7-amino-4-methylcoumarin
-
 ?
benzyloxycarbonyl-L-Arg-Arg-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens benzyloxycarbonyl-L-Arg-Arg + 7-amino-4-methylcoumarin
-
 ?
benzyloxycarbonyl-L-Phe-Arg-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens benzyloxycarbonyl-L-Phe-Arg + 7-amino-4-methylcoumarin
-
 ?
additional information cathepsin B is able to self-activate Homo sapiens ?
-
 ?
N-benzyloxycarbonyl-L-Leu-L-Arg 7-amido-4-methylcoumarin + H2O
-
 Homo sapiens benzyloxycarbonyl-L-Leu-L-Arg + 7-amino-4-methylcoumarin
-
 ?