Literature summary for 3.4.21.B7 extracted from

Dang, Y.F.; Shen, Y.B.; Xu, X.Y.; Wang, S.T.; Meng, X.Z.; Li, L.S.; Zhang, M.; Hu, M.Y.; Lv, L.Q.; Wang, R.Q.; Li, J.L.
Mannan-binding lectin-associated serine protease-1 (MASP-1) mediates immune responses against Aeromonas hydrophila invitro and invivo in grass carp (2017), Fish Shellfish Immunol., 66, 93-102 .

Search for more literature for 3.4.21.B7

Organism

Organism	UniProt	Comment	Textmining
Ctenopharyngodon idella	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	transcription is widely distributed in different tissues	Ctenopharyngodon idella	-

Expression

Organism	Comment	Expression
Ctenopharyngodon idella	transcription is induced by Aeromonas hydrophila in vivo and in vitro and also by lipopolysaccharide and flagellin stimulation in vitro	up

General Information

General Information	Comment	Organism
physiological function	in cells over-expressing gcMASP-1, transcript levels of almost all immune components, except gcMBL and gcC5, are significantly enhanced, and gcIL1beta, gcTNF-alpha, gcIFN, gcCD59, gcC5aR1, and gcITGb-2 are significantly upregulated after exposure to Aeromonas hydrophila. MASP-1 interference downregulates the transcript levels after Aeromonas hydrophila challenge. In addition, gcMASP-1 activates NF-kappaB signaling	Ctenopharyngodon idella

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)