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Literature summary for 3.4.21.B7 extracted from

  • Moller-Kristensen, M.; Thiel, S.; Sjoeholm, A.; Matsushita, M.; Jensenius, J.C.
    Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway (2007), Int. Immunol., 19, 141-149.
    View publication on PubMed
Search for more literature for 3.4.21.B7

Activating Compound

Activating Compound Comment Organism Structure
mannan-binding lectin
-
 Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK293 cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens MASP-1 shows no activity toward complement C4. MASP-1 collaborates with MASP-2 in the generation of C3 convertase, a process observable at high serum concentration, but not at low serum concentration ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
MBL-derivatized Sepharose column chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
 Homo sapiens
-
serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C2 + H2O
-
 Homo sapiens complement component C2b + ?
-
 ?
complement component C3 + H2O
-
 Homo sapiens complement component C3b + ?
-
 ?
additional information MASP-1 shows no activity toward complement C4. MASP-1 collaborates with MASP-2 in the generation of C3 convertase, a process observable at high serum concentration, but not at low serum concentration Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
MASP-1 MASP-1 collaborates with MASP-2 in the generation of C3 convertase Homo sapiens