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Literature summary for 3.4.21.B7 extracted from

  • Zundel, S.; Cseh, S.; Lacroix, M.; Dahl, M.R.; Matsushita, M.; Andrieu, J.P.; Schwaeble, W.J.; Jensenius, J.C.; Fujita, T.; Arlaud, G.J.; Thielens, N.M.
    Characterization of recombinant mannan-binding lectin-associated serine protease (MASP)-3 suggests an activation mechanism different from that of MASP-1 and MASP-2 (2004), J. Immunol., 172, 4342-4350.
    View publication on PubMed
Search for more literature for 3.4.21.B7

Cloned(Commentary)

Cloned (Comment) Organism
expression in a baculovirus/insect cells system Homo sapiens

Protein Variants

Protein Variants Comment Organism
S627A kinetic parameters similiar to wild type, mutant is activated by its active counterpart Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
EDTA inhibits binding of MASP-1 to immobilized mannan-binding lectin and L-ficolin/P35, when substituted for Ca2+ Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ provides binding of MASP-1 to immobilized mannan-binding lectin and L-ficolin/P35 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 SDS-PAGE and Western blot analysis, partially activated form Homo sapiens
90000
-
 SDS-PAGE and Western blot analysis, proenzyme form Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
MASP-1
-
 Homo sapiens