Application | Comment | Organism |
---|---|---|
additional information | MASP-1 enhances complement activation triggered by mannose-binding protein-MASP-2 complexes, but cannot initiate activation itself | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | MASP-1 ent, catalytically active form of MASP-1 produced by substituting residues 425Lys-His-Ile-Ser-Arg | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
8.9 | - |
benzoyl-L-arginine p-nitroanilide | cleavage by activated MASP-1 ent | Rattus norvegicus | |
13 | - |
complement C2 | cleavage by activated MASP-1 ent | Rattus norvegicus | |
13 | - |
complement C2 | complement component C2 | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
complement component C2 + H2O | Rattus norvegicus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
by affinity chromatography | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzoyl-L-arginine p-nitroanilide + H2O | - |
Rattus norvegicus | benzoyl-L-arginine + 4-nitroaniline | - |
? | |
complement component C2 + H2O | - |
Rattus norvegicus | ? | - |
? | |
additional information | no cleavage of complement C4 and N-alpha-carbobenzoxy-L-lysine p-nitropenhyl ester | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MASP-1 | - |
Rattus norvegicus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
3.9 | - |
Complement component C2 | cleavage by activated MASP-1 ent | Rattus norvegicus | |
4.3 | - |
benzoyl-L-arginine p-nitroanilide | cleavage by activated MASP-1 ent | Rattus norvegicus |