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Literature summary for 3.4.21.B7 extracted from

  • Thielens, N.M.; Cseh, S.; Thiel, S.; Vorup-Jensen, T.; Rossi, V.; Jensenius, J.C.; Arlaud, G.J.
    Interaction properties of human mannan-binding lectin (MBL)-associated serine proteases-1 and -2, MBL-associated protein 19, and MBL (2001), J. Immunol., 166, 5068-5077.
    View publication on PubMed
Search for more literature for 3.4.21.B7

Cloned(Commentary)

Cloned (Comment) Organism
expressed in insect or human kidney cells Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38000
-
 calculated molecular mass of the MASP-1 CUB-EGF fragment in the presence of Ca2+ Homo sapiens
58000
-
 1 * 58000 + 1 * 30000-32000, SDS-PAGE Homo sapiens
90000
-
 proenzyme Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens complexes with mannose-binding lectin in the presence of Ca2+, involved in activation of complement cascade ?
-
 ?
Protein + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification proenzyme is cleaved between Arg448 and Ile449 Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information complexes with mannose-binding lectin in the presence of Ca2+, involved in activation of complement cascade Homo sapiens ?
-
 ?
Protein + H2O
-
 Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
dimer 1 * 58000 + 1 * 30000-32000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
MASP-1
-
 Homo sapiens