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Literature summary for 3.4.21.B6 extracted from
- Evidence for a matriptase-prostasin proteolytic cascade regulating terminal epidermal differentiation (2006), J. Biol. Chem., 281, 32941-32945.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| matriptase | soluble matriptase efficiently converts soluble prostasin zymogen to an active two-chain form by endoproteolytic cleavage after Arg12 within the amino acid sequence QPR12-ITG | Mus musculus |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in HEK-293T cells | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Mus musculus | 16020 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 37000 | - |
SDS-PAGE, mature active enzyme | Mus musculus |
| 39000 | - |
SDS-PAGE, immature enzyme | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epidermis | - |
Mus musculus | - |
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Release 2023.1 (January 2023)
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