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Literature summary for 3.4.21.B6 extracted from
- Prostasin regulates epithelial monolayer function: cell-specific Gpld1-mediated secretion and functional role for GPI anchor (2006), Am. J. Physiol., 291, C1258-C1270.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in M-1 cells | Mus musculus |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| S238A | inactive | Mus musculus |
| S313N/S314L | lacks the preferred GPI attachment sites and shows decreased activity | Mus musculus |
| S313N/S314L/R322A | mutant alters both the preferred GPI attachment sites and the potential COOH-terminal tryptic cleavage site, activity is not different from wild type prostasin | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cell surface | prostasin is glycosylphosphatidylinositol-anchored to the cell surface | Mus musculus | 9986 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q99L44 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Mus musculus | - |
| lung epithelium | - |
Mus musculus | - |
| prostate gland | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CAP-1 | - |
Mus musculus |
| channel-activating protease 1 | - |
Mus musculus |
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Release 2023.1 (January 2023)
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