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BRENDA support

Literature summary for 3.4.21.B6 extracted from

  • Olivieri, O.; Castagna, A.; Guarini, P.; Chiecchi, L.; Sabaini, G.; Pizzolo, F.; Corrocher, R.; Righetti, P.G.
    Urinary prostasin: a candidate marker of epithelial sodium channel activation in humans (2005), Hypertension, 46, 683-688.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information increases in urine of patients affected by primary aldosteronism after volume expansion Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
saline reduces prostasin in nomotensive subjects Homo sapiens
spironolactone decreases urinary prostasin in nomotensives in whom the renin/aldosterone axis is activated by a low Na+ intake, ineffective in individuals with high Na+ intake Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
urine
-
Homo sapiens
-