Literature summary for 3.4.21.B43 extracted from

Talieri, M.; Devetzi, M.; Scorilas, A.; Pappa, E.; Tsapralis, N.; Missitzis, I.; Ardavanis, A.
Human kallikrein-related peptidase 12 (KLK12) splice variants expression in breast cancer and their clinical impact (2012), Tumour Biol., 33, 1075-1084.

Search for more literature for 3.4.21.B43

Application

Application	Comment	Organism
diagnostics	enzyme splice variant KLK12sv3 can be regarded as a marker of good prognosis in breast cancer	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
the gene is located on chromosome 19q13.4, splice variants KLK12sv3 and KLK12sv1/KLK12sv2 in breast cancer cells by quantitative real-time PCR as well as semi-quantitative PCR expression analysis	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9UKR0	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
breast cancer cell	enzyme splice variant KLK12sv3 is more frequently expressed in tumors of lower grade, early patient TNM stage, and smaller tumor size, overview	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
kallikrein-related peptidase 12	-	Homo sapiens
KLK12	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	expression profile of the splice variants KLK12sv3 and KLK12sv1/KLK12sv2 of kallikrein-related peptidase 12 in breast cancer patients and their clinical significance, overview. Positive KLK12sv3 expression is associated with longer patient disease-free survival and higher progesterone receptor concentration. KLK12sv1/KLK12sv2 expression is statistically associated with KLK12sv3 expression	Homo sapiens

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Release 2023.1 (January 2023)