Literature summary for 3.4.21.B4 extracted from

Guo, Y.; Chen, J.; Shi, L.; Fan, Z.
Valosin-containing protein cleavage by granzyme K accelerates an endoplasmic reticulum stress leading to caspase-independent cytotoxicity of target tumor cells (2010), J. Immunol., 185, 5348-5359.

Search for more literature for 3.4.21.B4

Inhibitors

Inhibitors	Comment	Organism	Structure
N-acetyl-YRFK-chloromethylketone	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N-acetyl-YRFK-4-nitroanilide + H2O	-	Homo sapiens	N-acetyl-YRFK + 4-nitroaniline	-	?

Synonyms

Synonyms	Comment	Organism
GzmK	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	valosin-containing protein cleavage by granzyme K accelerates an endoplasmic reticulum stress leading to caspase-independent cytotoxicity of target tumor cells	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)