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Literature summary for 3.4.21.B4 extracted from
- Granzyme K (2004), Handbook of Proteolytic Enzymes (Barrett, A. J. , Rawlings, N. D. , Woessner; j. F. , eds. )Academic Press, 2, 1552-1554.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3,4-dichloroisocoumarin | complete inhibition at 0.1 mM | Homo sapiens |  |
| Aprotinin | complete inhibition at 0.015 mM | Homo sapiens | |
| diisopropylfluorophosphate | complete inhibition at 0.1 mM | Homo sapiens | |
| inter-alpha-trypsin inhibitor | complete inhibition at 66 nM | Homo sapiens | |
| L-Phe-L-Pro-L-Arg-chloromethyl ketone | complete inhibition at 0.1 mM | Homo sapiens | |
| leupeptin | 50% inhibition at 0.2 mM | Homo sapiens | |
| phenylmethylsulfonyl fluoride | complete inhibition at 2 mM | Homo sapiens | |
| Tos-Lys-CH2Cl | complete inhibition at 0.1 mM | Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 25000 | - |
reducing SDS-PAGE | Homo sapiens |
| 28000 | - |
non-reducing SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lung | mRNA exptression | Homo sapiens | - |
| natural killer cell | mRNA exptression | Homo sapiens | - |
| spleen | mRNA exptression | Homo sapiens | - |
| thymus | mRNA exptression | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly + H2O | - |
Homo sapiens | Cys-Gly-Tyr-Gly-Pro-Lys + Lys-Lys-Arg + Lys-Val-Gly-Gly | - |
? | |
| Z-Arg-thiobenzyl ester + H2O | - |
Homo sapiens | Z-Arg + thiobenzyl alcohol | - |
? | |
| Z-Lys-thiobenzyl ester + H2O | - |
Homo sapiens | Z-Lys + thiobenzyl alcohol | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| granzyme 3 | - |
Homo sapiens |
| granzyme K | - |
Homo sapiens |
| granzyme K | - |
Rattus norvegicus |
| RNK-Tryp-2 | - |
Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Homo sapiens |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Homo sapiens | predicted from sequence | - |
10.2 |
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