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Literature summary for 3.4.21.B39 extracted from

  • Britland, S.; Hoyle, M.
    Transcriptional gene silencing of kallikrein 5 and kallikrein 7 using siRNA prevents epithelial cell detachment induced by alkaline shock in an in vitro model of eczema (2011), Biotechnol. Prog., 28, 485-489.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
lymphoepithelial Kazal-type 5 serine protease inhibitor
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
desmocollin-3 + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HaCaT cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
desmocollin-3 + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
kallikrein 5
-
Homo sapiens
KLK5
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens kallikrein 5 has increased activity levels in eczematous lesions up

General Information

General Information Comment Organism
physiological function kallikrein 5 is implicated in the destruction of corneodesomosomes Homo sapiens