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Literature summary for 3.4.21.B39 extracted from

  • Mavridis, K.; Talieri, M.; Scorilas, A.
    KLK5 gene expression is severely upregulated in androgen-independent prostate cancer cells after treatment with the chemotherapeutic agents docetaxel and mitoxantrone (2010), Biol. Chem., 391, 467-474.
    View publication on PubMed

Application

Application Comment Organism
diagnostics KLK5 is a promising biomarker for prostate cancer diagnosis and prognosis Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
KLK5 quantitative real-time PCR expression analysis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9Y337
-
-

Source Tissue

Source Tissue Comment Organism Textmining
DU-145 cell
-
Homo sapiens
-
prostate cancer cell
-
Homo sapiens
-
prostate cancer cell line
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
KLK5
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens KLK5 gene expression is severely upregulated in androgen-independent prostate cancer cells after treatment with the chemotherapeutic agents docetaxel and mitoxantrone up

General Information

General Information Comment Organism
additional information potential role of endogenous KLK5 expression in supporting CaP cells to cope with the cytostatic phenomena induced by chemotherapeutic agents practiced in standard first-line CaP chemotherapy Homo sapiens