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Literature summary for 3.4.21.B39 extracted from
- Identification of lympho-epithelial Kazal-type inhibitor 2 in human skin as a kallikrein-related peptidase 5-specific protease inhibitor (2009), PLoS ONE, 4, e4372.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| SPINK9 | i.e. LEKTI-2. Inhibits KLK5 but not KLK7, 14 or other serine proteases tested including trypsin, plasmin and thrombin. LEKTI-2 contributes to the regulation of the desquamation process in human skin by specifically inhibiting KLK5 | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N(p-tosyl)-Arg-Gly-Val 4-nitroanilide | - |
Homo sapiens | ? | - |
? |  |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.000257 | - |
SPINK9 | pH 8, 21°C | Homo sapiens |
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