Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | transmembrane-anchored | Mus musculus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
complement C1q tumor necrosis factor-related protein 6 + H2O | Mus musculus | cleavage at position 26 after a Val-Pro sequence | ? | - |
? | |
CXCL-5 + H2O | Mus musculus | processing of CXCL-5 at position 42, which is after an Ala-Pro sequence | ? | - |
? | |
extracellular matrix protein 1 + H2O | Mus musculus | cleavage occurrs at position 142 after a Lys-Pro sequence | ? | - |
? | |
extracellular matrix protein CN-I + H2O | Mus musculus | - |
? | - |
? | |
extracellular matrix protein CN-III + H2O | Mus musculus | - |
? | - |
? | |
extracellular matrix protein CN-V + H2O | Mus musculus | - |
? | - |
? | |
fibrillin-2 + H2O | Mus musculus | cleavage occurrs at position 60, in the propeptide domain, after a Gly-Pro sequence | ? | - |
? | |
lysyl oxidase homolog 2 + H2O | Mus musculus | cleavage at position 36 after a Tyr-Pro sequence that follows the signal peptide | ? | - |
? | |
additional information | Mus musculus | the enzyme has both dipeptidyl aminopeptidase and endopeptidase activities, and can hydrolyze the post-proline bond | ? | - |
? | |
Type I collagen + H2O | Mus musculus | - |
? | - |
? | |
type III collagen + H2O | Mus musculus | - |
? | - |
? | |
type V collagen + H2O | Mus musculus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | expression is very low in adult organs, but is upregulated by activated fibroblasts in sites of tissue remodeling, including fibrosis, atherosclerosis, arthritis and tumors | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
complement C1q tumor necrosis factor-related protein 6 + H2O | cleavage at position 26 after a Val-Pro sequence | Mus musculus | ? | - |
? | |
CXCL-5 + H2O | processing of CXCL-5 at position 42, which is after an Ala-Pro sequence | Mus musculus | ? | - |
? | |
extracellular matrix protein 1 + H2O | cleavage occurrs at position 142 after a Lys-Pro sequence | Mus musculus | ? | - |
? | |
extracellular matrix protein CN-I + H2O | - |
Mus musculus | ? | - |
? | |
extracellular matrix protein CN-III + H2O | - |
Mus musculus | ? | - |
? | |
extracellular matrix protein CN-V + H2O | - |
Mus musculus | ? | - |
? | |
fibrillin-2 + H2O | cleavage occurrs at position 60, in the propeptide domain, after a Gly-Pro sequence | Mus musculus | ? | - |
? | |
lysyl oxidase homolog 2 + H2O | cleavage at position 36 after a Tyr-Pro sequence that follows the signal peptide | Mus musculus | ? | - |
? | |
additional information | the enzyme has both dipeptidyl aminopeptidase and endopeptidase activities, and can hydrolyze the post-proline bond | Mus musculus | ? | - |
? | |
Type I collagen + H2O | - |
Mus musculus | ? | - |
? | |
type III collagen + H2O | - |
Mus musculus | ? | - |
? | |
type V collagen + H2O | - |
Mus musculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
fibroblast activation protein-alpha | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | plasma from FAP-deficient mice exhibits slower than wild-type clotting times | Mus musculus |