Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | integral membrane protein | Homo sapiens | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
BT-549 cell | - |
Homo sapiens | - |
fibroblast | expressed in most stromal fibroblasts | Homo sapiens | - |
MCF-7 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
FAPalpha | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme promotes cell growth, adhesion, invasion and migration in breast cancer. Its regulatory effects are independent of its enzymatic activity. The PI3K/AKT and MMP2/9 signaling pathway might be involved in the effects of FAPalpha on breast cancer cells | Homo sapiens |