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Literature summary for 3.4.21.B28 extracted from

  • Collins, P.J.; McMahon, G.; OBrien, P.; OConnor, B.
    Purification, identification and characterisation of seprase from bovine serum (2004), Int. J. Biochem. Cell Biol., 36, 2320-2333.
    View publication on PubMed
Search for more literature for 3.4.21.B28

Inhibitors

Inhibitors Comment Organism Structure
diisopropylfluorophosphate irreversible inhibition Bos taurus
additional information not inhibited by JTP-4819, Fmoc-Ala-pyrrCN and N-benzyloxycarbonyl-Phe-Pro-BT Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.27
-
 Z-Gly-Pro-4-methylcoumarin-7-amide
-
 Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
by column chromatographies, 30197fold to homogeneity Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
blood serum
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
 Bos taurus ?
-
 ?
additional information no hydrolysis of Pro-7-amino-4-methylcoumarin, Gly-Pro-7-amino-4-methylcoumarin, Ala-Pro-7-amino-4-methylcoumarin, pGly-His-Pro-7-amino-4-methylcoumarin, N-benzyloxycarbonyl-Pro-Phe, Gly-Gly-Pro-Ala and N-benzyloxycarbonyl-Gly-Leu-Phe-His Bos taurus ?
-
 ?
N-benzyloxycarbonyl-Gly-Leu-Phe-His + H2O
-
 Bos taurus ?
-
 ?
N-benzyloxycarbonyl-Gly-Pro-7-amido-4-methylcoumarin + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + 7-amino-4-methylcoumarin
-
 ?
N-benzyloxycarbonyl-Gly-Pro-Ala + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + L-Ala
-
 ?
N-benzyloxycarbonyl-Gly-Pro-Glu + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + L-Glu
-
 ?
N-benzyloxycarbonyl-Gly-Pro-His + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + L-His
-
 ?
N-benzyloxycarbonyl-Gly-Pro-Leu + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + L-Leu
-
 ?
N-benzyloxycarbonyl-Gly-Pro-Met + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + L-Met
-
 ?
N-benzyloxycarbonyl-Gly-Pro-Met-His + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + Met-His
-
 ?
N-benzyloxycarbonyl-Gly-Pro-Met-His-Arg-Ser + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + Met-His-Arg-Ser
-
 ?
N-benzyloxycarbonyl-Gly-Pro-Phe + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + L-Phe
-
 ?
N-benzyloxycarbonyl-Gly-Pro-Phe-His + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + L-Phe-L-His
-
 ?
N-benzyloxycarbonyl-Gly-Pro-Phe-His-Arg + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + Phe-His-Arg
-
 ?
N-benzyloxycarbonyl-Gly-Pro-Phe-His-Arg-Ser + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + Phe-His-Arg-Ser
-
 ?
N-benzyloxycarbonyl-Gly-Pro-Ser + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + L-Ser
-
 ?
N-benzyloxycarbonyl-Gly-Pro-Tyr + H2O
-
 Bos taurus N-benzyloxycarbonyl-Gly-Pro + L-Tyr
-
 ?

Synonyms

Synonyms Comment Organism
fibroblast activation protein alpha
-
 Bos taurus
seprase
-
 Bos taurus
Z-Pro-prolinal-insensitive peptidase
-
 Bos taurus
ZIP
-
 Bos taurus