Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | inhibition at 140 mM | Homo sapiens | |
chymostatin | 50% inhibition at 0.16 mM | Homo sapiens | |
dimethyl sulfoxide | 50% inhibition at 4% | Homo sapiens | |
dithiothreitol | inhibition at 10 mM | Homo sapiens | |
phenylmethylsulfonyl fluoride | more than 50% inhibition at 1 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.2 | - |
Ala-Pro-4-trifluoromethylcoumarin-7-amide | pH 8.5 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q12884 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | two isoforms: glycosylated and nonglycosylated | Homo sapiens |
Purification (Comment) | Organism |
---|---|
glycosylated form, near homogeneity | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Ala-Pro-4-trifluoromethylcoumarin-7-amide + H2O | - |
Homo sapiens | Ala-Pro + 7-amino-4-trifluoromethylcoumarin | - |
? | |
additional information | glycosylated form has both postprolyl depeptidyl peptidase and postgelatinase activity, nonglycosylated isoform has no detectable gelatinase activity | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FAP | - |
Homo sapiens |
fibroblast activation factor | - |
Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2 | - |
Ala-Pro-4-trifluoromethylcoumarin-7-amide | pH 8.5 | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | 9 | - |
Homo sapiens |