Literature summary for 3.4.21.B27 extracted from

Turpeinen, H.; Oksanen, A.; Kivinen, V.; Kukkurainen, S.; Uusimaeki, A.; Raemet, M.; Parikka, M.; Hytoenen, V.P.; Nykter, M.; Pesu, M.
Proprotein convertase subtilisin/kexin type 7 (PCSK7) is essential for the zebrafish development and bioavailability of transforming growth factor beta1a (TGFbeta1a) (2013), J. Biol. Chem., 288, 36610-36623.

Search for more literature for 3.4.21.B27

Cloned(Commentary)

Cloned (Comment)	Organism
gene pcsk7, DNA and amino acid sequence determination and analysis, sequence comparison,expression analysis	Danio rerio

Organism

Organism	UniProt	Comment	Textmining
Danio rerio	F1R440	gene pcsk7	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
larva	-	Danio rerio	-
additional information	the enzyme is ubiquitously expressed and evident already during the early development, enzyme expression during the first week of fish development and in several tissues, overview	Danio rerio	-

Synonyms

Synonyms	Comment	Organism
PCSK7	-	Danio rerio
proprotein convertase subtilisin/kexin type 7	-	Danio rerio

General Information

General Information	Comment	Organism
malfunction	inhibiting the enzyme in zebrafish results in various developmental defects and dysregulation of gene expressions, phenotypes, overview	Danio rerio
additional information	homology structure modeling, overview	Danio rerio
physiological function	the enzyme is essential for zebrafish development and regulates the expression and proteolytic cleavage of transforming growth factor beta1a	Danio rerio

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Release 2023.1 (January 2023)