Literature summary for 3.4.21.B27 extracted from

Leonhardt, R.; Fiegl, D.; Rufer, E.; Karger, A.; Bettin, B.; Knittler, M.
Post-endoplasmic reticulum rescue of unstable MHC class I requires proprotein convertase PC7 (2010), J. Immunol., 184, 2985-2998.

Search for more literature for 3.4.21.B27

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Homo sapiens	16020	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lymphoblastoid cell line	T2	Homo sapiens	-

Subunits

Subunits	Comment	Organism
?	x * about 90000, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
PC7	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	cells silenced for proprotein convertase 7 have substantially reduced MHC class I surface levels caused by high instability and significantly delayed surface accumulation of these molecules	Homo sapiens
physiological function	proprotein convertase 7 is required for normal MHC class I surface levels in the context of a defective peptide-loading complex	Homo sapiens

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Release 2023.1 (January 2023)