Literature summary for 3.4.21.B27 extracted from

Zhong, M.; Munzer, J.S.; Basak, A.; Benjannet, S.; Mowla, S.J.; Decroly, E.; Chretien, M.; Seidah, N.G.
The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity (1999), J. Biol. Chem., 274, 33913-33920.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
N-terminal pro-segment of PC7	inhibits its parent enzyme, 50% inhibition at 0.0000004 mM	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
12350	-	MALDI-TOF mass spectroscopy	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Rattus norvegicus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
human immunodeficiency virus envelope glycoprotein pg160 + H2O	-	Rattus norvegicus	?	-	?
pERTKR-4-methylcoumarin 7-amide + H2O	-	Rattus norvegicus	pERTKR + 7-amino-4-methylcoumarin	-	?

Synonyms

Synonyms	Comment	Organism
PC7	-	Rattus norvegicus
S08.077	Merops ID	Rattus norvegicus

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Release 2023.1 (January 2023)