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Literature summary for 3.4.21.B21 extracted from

  • Miao, D.; Fenno, J.C.; Timm, J.C.; Joo, N.E.; Kapila, Y.L.
    The Treponema denticola chymotrypsin-like protease dentilisin induces matrix metalloproteinase-2-dependent fibronectin fragmentation in periodontal ligament cells (2011), Infect. Immun., 79, 806-811.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.B21

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane outer membrane Treponema denticola 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fibronectin + H2O Treponema denticola
-
 ?
-
 ?
Fibronectin + H2O Treponema denticola MHE
-
 ?
-
 ?
Gelatin + H2O Treponema denticola
-
 ?
-
 ?
Gelatin + H2O Treponema denticola MHE
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Treponema denticola
-
-
-
Treponema denticola MHE
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fibronectin + H2O
-
 Treponema denticola ?
-
 ?
Fibronectin + H2O
-
 Treponema denticola MHE ?
-
 ?
Gelatin + H2O
-
 Treponema denticola ?
-
 ?
Gelatin + H2O
-
 Treponema denticola MHE ?
-
 ?
succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine-4-nitroanilide + H2O
-
 Treponema denticola succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine + 4-nitroaniline
-
 ?
succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine-4-nitroanilide + H2O
-
 Treponema denticola MHE succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine + 4-nitroaniline
-
 ?

Synonyms

Synonyms Comment Organism
dentilisin
-
 Treponema denticola
PrtP protease
-
 Treponema denticola

General Information

General Information Comment Organism
physiological function Treponema denticola acylated outer membrane PrtP protease complex induces both activation of MMP-2 and generation of fibronectin fragments in human PDL cell culture supernatants Treponema denticola