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Literature summary for 3.4.21.B10 extracted from

  • Talieri, M.; Zoma, M.; Devetzi, M.; Scorilas, A.; Ardavanis, A.
    Kallikrein-related peptidase 6 (KLK6) gene expression in intracranial tumors (2012), Tumour Biol., 33, 1375-1383.
    View publication on PubMed
Search for more literature for 3.4.21.B10

Application

Application Comment Organism
diagnostics kallikrein-related peptidases are biomarkers for prognosis, diagnosis and therapeutic intervention of cancer. KLK6 gene expression may have clinical utility as a marker of unfavorable prognosis for intracranial tumors Homo sapiens
medicine the enzyme might be useful as target for therapeutic intervention in case of intracranial tumors Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
gene KLK6, quantitative real-time PCR expression analysis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q92876 gene KLK6
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Source Tissue

Source Tissue Comment Organism Textmining
astrocytoma cell
-
 Homo sapiens
-
brain high expression level Homo sapiens
-
choroid plexus papilloma cell
-
 Homo sapiens
-
ependymoma cell grade II Homo sapiens
-
glioblastoma cell
-
 Homo sapiens
-
haemaglioblastoma cell
-
 Homo sapiens
-
intracranial tumor cell 73 intracranial tumor samples are screened for enzyme expression by quantitative real-time PCR analysis, overview Homo sapiens
-
meningioma cell
-
 Homo sapiens
-
additional information the enzyme is expressed more frequently in tumors of high malignancy, like the glioblastomas, and less in tumors of low malignancy, like the meningiomas. No expression in cell lines U-251-MG and D-54 Homo sapiens
-
myeloblastoma cell
-
 Homo sapiens
-
neurinoma cell
-
 Homo sapiens
-
non-Hodgkin lymphoma cell
-
 Homo sapiens
-
oligodendroglioma cell
-
 Homo sapiens
-
osteoma cell
-
 Homo sapiens
-
SH-SY5Y cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
kallikrein-related peptidase 6
-
 Homo sapiens
KLK6
-
 Homo sapiens