Literature summary for 3.4.21.B10 extracted from

Ni, X.; Zhang, W.; Huang, K.C.; Wang, Y.; Ng, S.K.; Mok, S.C.; Berkowitz, R.S.; Ng, S.W.
Characterisation of human kallikrein 6/protease M expression in ovarian cancer (2004), Br. J. Cancer, 91, 725-731.

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Application

Application	Comment	Organism
medicine	developoment of a monoclonal antibody to conform the high expression level of hK6 in ovarian tumor cells. The development of high-quality monoclonal antibodies will facilitate the evaluation of biomarkers and allow further screening tool development for early detection of avarian cancer	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
ovary cancer cell	gene amplification is one mechanism for the overexpression of hK6 in ovarian cancer. High expression of hK6 protein in coexisting benign, borderline and invasive ovarian tumours is observed. The tumours also express high levels of kallikrein 6 mRNA	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
hK6	-	Homo sapiens

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Release 2023.1 (January 2023)