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Literature summary for 3.4.21.98 extracted from

  • DæSouza, E.D.A.; Grace, K.; Sangar, D.V.; Rowlands, D.J.; Clarke, B.E.
    In vitro cleavage of hepatitis C virus polyprotein substrates by purified recombinant NS3 protease (1995), J. Gen. Virol., 76, 1729-1736.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Hepacivirus C

Inhibitors

Inhibitors Comment Organism Structure
N-tosyl-Phe chloromethyl ketone
-
Hepacivirus C
Nalpha-p-tosyl-Lys chloromethyl ketone
-
Hepacivirus C

Organism

Organism UniProt Comment Textmining
Hepacivirus C
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Hepacivirus C

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information ATPase activity Hepacivirus C ?
-
?
non-structural protein NS5B of hepatitis C virus + H2O
-
Hepacivirus C ? + DDIVPC-OH
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
-
Hepacivirus C