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Literature summary for 3.4.21.98 extracted from
- Canine hepacivirus NS3 serine protease can cleave the human adaptor proteins MAVS and TRIF (2012), PLoS ONE, 7, e42481.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| canine hepacivirus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| human mitochondrial antiviral signaling protein + H2O | - |
canine hepacivirus | ? | - |
? |  |
| Toll-IL-1 receptor domain-containing adaptor inducing interferon-beta + H2O | - |
canine hepacivirus | ? | - |
? | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | canine hepacivirus protease can disrupt the human innate antiviral defense signaling pathway suggesting a possible evolutionary relationship between canine hepacivirus and hepatitis C virus | canine hepacivirus |
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Release 2023.1 (January 2023)
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